🐯 Ultra Sensitive Psa Vs Regular Psa

Purpose With the availability of ultra-sensitive PSA assays, early biochemical relapse (eBCR) of prostate cancer is increasingly being detected at values much lower than the conventional threshold of 0.2 ng/ml. Accurate localisation of disease in this setting may allow treatment modification and improved outcomes, especially in patients with pelvis-confined or extra-pelvic oligometastasis The ultra sensitive tests can indicate recurrence in lower that usual PSA levels, however, at such tinny PSA fractions there is no rule indicating that a patient will do better in terms of survival with a salvage done when the PSA is 0.05 than when it reaches 0.07. Within 10 years of RP, the immediate versus delayed PSA groups differed in the receipt of salvage therapy (81% vs. 46%), as well as ACM (11% vs. 6%), PCSM (6% vs. 3%) and MFS (79% vs. 92%). A high Decipher genomic classifier score, increasing CAPRA-S score, and PSA doubling time of less than six months were associated with a greater likelihood There is a very commonly used scale of cancer probability used by urologists based on PSA vs. free PSA. The 50% chance stems from the <10% free PSA in the above results. % Free PSA is a more specific indicator for malignancy than Total PSA. Just had my 9 month PSA test and it is still undetectable. There are other things to consider like tumor volume, pre surgery PSA and Gleason score. The waiting is the worst. Also, be aware that even if the first test does show some detectable PSA that it might mean that some prostate tissue was left behind and is still producing PSA. The test is very sensitive and can pick up small changes in PSA levels. Doctors will usually want to know how quickly levels of PSA in the blood are rising. To find this out, a person will need to Both the American Urological Association and the American Society of Radiation Oncology recommend that salvage radiation be given when PSA levels reach or exceed 0.2 ng/mL. But Tendulkar says that level was defined years ago, before ultra-sensitive methods for detecting PSA became widely available. I have a lot of PSA anxiety, rightly so, since this is what led me to surgery in the first place! I may first go with the normal PSA. If I am lucky enough to get "< 0.1 - undetectable" for one or two PSA tests, I feel I can always switch to the ultra-sensitive variety at a later time. I understand your anxiety over this. Many of us (me included) have found that undetectable results of <0.006 (and low readings a bit higher) are now being reported by Labcorp as <0.014. I got no reply when I asked Labcorp about this through their patient portal. This is from a ROCHE spec sheet (updated 28.10.2020) for their PSA assay, which Labcorp uses: Detection Limits. nM3S.

ultra sensitive psa vs regular psa